Stannous Chloride → Ethyl 3-(3-aminophenyl)-3-(2-phenylbutyrylamino)-propionate

HRID 1596579

반응식

HRID 1596579 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]([NH:17][C:18](=[O:28])[CH:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:20][CH3:21])[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:7]=[CH:8][CH:9]=1)([O-])=O.[Sn](Cl)Cl>>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]([NH:17][C:18](=[O:28])[CH:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:20][CH3:21])[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:7]=[CH:8][CH:9]=1

참가 물질

3

반응물 2

HCID 24479Stannous ChlorideHCID 18505409Ethyl 3-(3-nitrophenyl)-3-(2-phenylbutyrylamino)-propionate

생성물 1

HCID 18505398Ethyl 3-(3-aminophenyl)-3-(2-phenylbutyrylamino)-propionate

실험 절차

Corresponding to Example 3b, 6.3 g of (7a) were reduced using tin-(II) dichloride. A white solid was obtained (yield: 3.9 g).

후처리

  1. customA white solid was obtained (yield: 3.9 g)

출처 및 근거

ORD 기록
ord-b68cc9f9bdc64f529ceefc78ccb467ef
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06291503B1

연결된 노트

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