Sodium Hydroxide → 4-(Pyridin-4-yl)butanoyl-sarcosine
반응식
C([O:3][C:4](=[O:19])[CH2:5][N:6]([C:8](=[O:18])[CH2:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1)[CH3:7])C.[OH-].[Na+]>CCO>[N:15]1[CH:14]=[CH:13][C:12]([CH2:11][CH2:10][CH2:9][C:8]([N:6]([CH2:5][C:4]([OH:19])=[O:3])[CH3:7])=[O:18])=[CH:17][CH:16]=1참가 물질
4
실험 절차
Ester 6-1 (324 mg, 1.22 mmol) was dissolved in 6 mL EtOH, then 1 N NaOH (2.4 mL, 2.4 mmol) was added. After stirring overnight the mixture was concentrated, rediluted with EtOAc, extracted into 10% KHSO4, then concentrated, providing acid 6-2, along with inorganic salts.
후처리
- concentrationwas concentrated
- additionrediluted with EtOAc
- extractionextracted into 10% KHSO4
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-a5515b61493b4f96bc3379e8cfaad037
- 출처 데이터셋
- uspto-grants-2001_09
- 특허 번호
- US06294549B1
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