1-Bromo-2-methylpropane → HCID 21700664, 화합물
반응식
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[C:10]=1[CH3:18])=[O:7].[OH-].[K+].Br[CH2:22][CH:23]([CH3:25])[CH3:24]>CS(C)=O>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[C:10]=1[CH3:18])=[O:7]참가 물질
5
실험 절차
The N-(2-furoyl)-2-methyl-3-nitroaniline (1 mmol) in DMSO was treated with potassium hydroxide (2.0 mmol) and 1-bromo-2-methylpropane (1.1 mmol) at 25° C. for 12 hr. Extraction and chromatography afforded N-(2-furoyl)-N-isobutyl-2-methyl-3-nitroaniline as a yellow syrup. TLC: Rf=0.40, 30% EtOAc-hexane.
후처리
- extractionExtraction and chromatography
출처 및 근거
- ORD 기록
- ord-a672711367ba4005a1fee29d7c327a64
- 출처 데이터셋
- uspto-grants-2001_09
- 특허 번호
- US06294672B1
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