Formic Acid → 3-Formylaminophenol

반응식

[NH2:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[CH:9](O)=[O:10]>>[CH:9]([NH:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1)=[O:10]

참가 물질

반응물 2

HCID 284Formic Acid

HCID 115683-Aminophenol

생성물 1

HCID 23843793-Formylaminophenol수율 93.1%

실험 절차

A mixture of 100 g m-aminophenol and 150 g formic acid was refluxed for 1.5 h and then evaporated to dryness under reduced pressure (90°-95° C., 10-15 mm Hg). Solid material was dried at 100° C., 10 mm Hg, for 1.5 h. 117 g of the title compound were isolated, melting point 112° C.

후처리

temperaturewas refluxed for 1.5 h
customevaporated to dryness under reduced pressure (90°-95° C., 10-15 mm Hg)
customSolid material was dried at 100° C.

출처 및 근거

ORD 기록: ord-bc624360872240eab7104b564913aeef
출처 데이터셋: uspto-grants-1998_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05739318

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