2-(N-ethyl-m-toluidino)ethanol → 2-(N-Ethyl-m-toluidino)ethyl benzoate

HRID 1599198노트

반응식

HRID 1599198 반응식
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:10]([N:12]([CH2:20][CH2:21][OH:22])[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([CH3:19])[CH:14]=1)[CH3:11]>CC(C)=O.N1C=CC=CC=1>[CH3:19][C:15]1[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=1)[N:12]([CH2:10][CH3:11])[CH2:20][CH2:21][O:22][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 2

HCID 70672-(N-ethyl-m-toluidino)ethanolHCID 7412Benzoyl chloride

생성물 1

HCID 30162602-(N-Ethyl-m-toluidino)ethyl benzoate

시약·촉매·용매 2

HCID 180Acetone용매HCID 1049Pyridine용매

실험 절차

Benzoylchloride (3.3 g) was added to a mixture of N-ethyl-N-hydroxyethyl-3-methylaniline (2.1 g) in acetone (25 cm3) and pyridine (1 cm3) and stirred at reflux for 1 hour. The reaction mixture was cooled and used directly in iv) below.

후처리

  1. temperatureat reflux for 1 hour
  2. temperatureThe reaction mixture was cooled

출처 및 근거

ORD 기록
ord-8bb22e8b3b4743d79c25ce656d2612d5
출처 데이터셋
uspto-grants-1998_04
특허 번호
US05739299

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