Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propylene Oxide → Gadoteridol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propylene Oxide | HCID 6378 | — |
| 반응물 | Gadolinium | HCID 23982 | — |
| 반응물 | 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt | HCID 10862527 | — |
| 생성물 | Gadoteridol | HCID 60714 | — |
반응 단계
The solution of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid sodium salt is directly reacted, as described in EP 292689, with propylene oxide to give the alkylated product, which can easily be complexed with gadolinium to give the final Gadoteridol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05977353 |
| 출처 데이터셋 | uspto-grants-1999_11 |
| ORD ID | ord-b8c2b92330a14aa49e05781c3b6833d4 |
| 출처 메모 | uspto-grants-1999_11 |