Dimethyl Sulfoxide → 2,3-Dihydro-2,2-dimethyl-4-benzofurancarboxaldehyde

HRID 1602451노트

반응식

HRID 1602451 반응식
[CH3:1][C:2]1([CH3:13])[CH2:6][C:5]2=[C:7]([CH2:11][OH:12])[CH:8]=[CH:9][CH:10]=[C:4]2[O:3]1.CS(C)=O.C(Cl)(=O)C(Cl)=O>C(N(CC)CC)C>[CH3:1][C:2]1([CH3:13])[CH2:6][C:5]2=[C:7]([CH:11]=[O:12])[CH:8]=[CH:9][CH:10]=[C:4]2[O:3]1

참가 물질

5

반응물 3

HCID 679Dimethyl SulfoxideHCID 65578Oxalyl chlorideHCID 18787456HCID 18787456, 화합물

생성물 1

HCID 187874682,3-Dihydro-2,2-dimethyl-4-benzofurancarboxaldehyde수율 122.8%

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

2,2-Dimethyl-2,3-dihydro-benzofuran-4-methanol (7.35 g, 41 mmol) was oxidized using DMSO, oxalyl chloride, and triethyl amine similar to the above procedures to give the product as a clear oil (8.87 g, 100%).

출처 및 근거

ORD 기록
ord-6660ae1e156b46408ba0481b60f50def
출처 데이터셋
uspto-grants-1999_11
특허 번호
US05981571

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