2-Heptanol → 2-Heptyl butyrate

HRID 1604136

반응식

HRID 1604136 반응식
[CH3:1][CH:2]([OH:8])[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]>C(OC(=O)CCC)(=O)CCC>[C:2]([O:8][CH:2]([CH3:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])(=[O:8])[CH2:3][CH2:4][CH3:5]

참가 물질

3

반응물 1

HCID 109762-Heptanol

생성물 1

HCID 5294962-Heptyl butyrate수율 85%

시약·촉매·용매 1

HCID 7798Butyric anhydride용매

실험 절차

Butyric anhydride (260 ml, Aldrich) was added to 2-heptanol (162 g, 1.4 mol, Aldrich) over a 1.5 hour period at 100-140° C. The mixture was heated to 160° for 4 hours. The reaction mixture was then cooled, washed with hot water, washed with aqueous sodium carbonate to remove butyric anhydride, dried over sodium sulfate, and then concentrated. Fractional distillation of the crude residue under vacuum provided 1-methylhexyl butyrate (85-110°/78-80 mm Hg, 85% yield), the structure of which was confirmed by mass spectroscopy, nuclear magnetic resonance spectroscopy, and infra red spectroscopy (not shown).

후처리

  1. temperatureThe mixture was heated to 160° for 4 hours
  2. temperatureThe reaction mixture was then cooled
  3. washwashed with hot water
  4. washwashed with aqueous sodium carbonate
  5. customto remove butyric anhydride
  6. dry with materialdried over sodium sulfate
  7. concentrationconcentrated
  8. distillationFractional distillation of the crude residue under vacuum

출처 및 근거

ORD 기록
ord-4635c16b95d14734bc4f70c31d9877c9
출처 데이터셋
uspto-grants-1999_11
특허 번호
US05993879

연결된 노트

불러오는 중…