Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Epoxybutane → 3-Phenyl-2(S)-phthalimidopropan-1-al
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Epoxybutane | HCID 7834 | — |
| 반응물 | 3-phenyl-2(S)-phthalimidopropionyl chloride | HCID 10567197 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3-Phenyl-2(S)-phthalimidopropan-1-al | HCID 11065801 | — |
반응 단계
The solution containing the 3-phenyl-2(S)-phthal-imidopropionyl chloride was diluted with 500 ml of toluene and combined with 72.11 g of 1,2-butylene oxide. 23.5 g of palladium on carbon (5%) and 100 ml of toluene were added to the solution. The suspension was hydrogenated for 17 hours with stirring and then filtered and the residue washed with 200 ml of toluene, wherein 3-phenyl-2(S)-phthalimidopropan-1-al was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05994555 |
| 출처 데이터셋 | uspto-grants-1999_11 |
| ORD ID | ord-48d3e33722a84601ad0fa0268b32d2cf |
| 출처 메모 | uspto-grants-1999_11 |