Perillaldehyde → Perilla alcohol

HRID 1604756

반응식

HRID 1604756 반응식
CC1CC[C@@H](C(C)=C)CC=1.[Se](=O)=O.[CH3:14][C:15]([CH:17]1[CH2:22][CH:21]=[C:20]([CH:23]=[O:24])[CH2:19][CH2:18]1)=[CH2:16]>[O-2].[O-2].[O-2].[Cr+6]>[CH3:16][C:15]([C@@H:17]1[CH2:18][CH:19]=[C:20]([CH2:23][OH:24])[CH2:21][CH2:22]1)=[CH2:14]

참가 물질

5

반응물 3

HCID 16441Perillaldehyde2회HCID 24007Selenium DioxideHCID 440917(+)-Limonene

생성물 1

HCID 369312Perilla alcohol

시약·촉매·용매 1

HCID 10219390chromium (VI) trioxide촉매

실험 절차

Perillyl alcohol can be produced by reacting limonene with selenium dioxide (that is toxic) and other oxidants (that are difficult to work with i.e., anhydrous chromium trioxide) to yield various oxidation products, including a small amount of perillaldehyde. Once isolated, perillaldehyde is reduced to afford perillyl alcohol. While this two-step process is conceptually attractive, the oxidation of limonene to give perillyl alcohol proceeds in a low overall yield.

후처리

  1. customto yield various oxidation products
  2. customOnce isolated

출처 및 근거

ORD 기록
ord-efc8b7b2544149a1a9a6fdf90618994b
출처 데이터셋
uspto-grants-1999_11
특허 번호
US05994598

연결된 노트

불러오는 중…