Pyrrolidine → 1-[(4-Bromo-2-fluorophenyl)carbonyl]pyrrolidine
반응식
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([F:11])[CH:3]=1.[NH:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:8])=[C:4]([F:11])[CH:3]=1참가 물질
3
실험 절차
The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluoro-benzoic acid and pyrrolidine.)
출처 및 근거
- ORD 기록
- ord-ec04af704dab4af0a800e52e05e90ec9
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07737135B2
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