2,3-dihydro-6-methoxy-2-(3-pyridylmethyl)-1H-isoindole-1-one → 2,3-dihydro-6-hydroxy-2-(3-pyridylmethyl)-1H-isoindole-1-one

HRID 1609598노트

반응식

HRID 1609598 반응식
C[O:2][C:3]1[CH:11]=[C:10]2[C:6]([CH2:7][N:8]([CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:9]2=[O:12])=[CH:5][CH:4]=1>Br>[OH:2][C:3]1[CH:11]=[C:10]2[C:6]([CH2:7][N:8]([CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:9]2=[O:12])=[CH:5][CH:4]=1

참가 물질

3

반응물 1

HCID 200820092,3-dihydro-6-methoxy-2-(3-pyridylmethyl)-1H-isoindole-1-one

생성물 1

HCID 200819992,3-dihydro-6-hydroxy-2-(3-pyridylmethyl)-1H-isoindole-1-one

시약·촉매·용매 1

HCID 260Hydrogen Bromide용매

실험 절차

The titled compound was prepared in the same manner as in Example 10 (1) b) by refluxing 2,3-dihydro-6-methoxy-2-(3-pyridylmethyl)-1H-isoindole-1-one in 47% hydrogen bromide under heating.

후처리

  1. temperatureunder heating

출처 및 근거

ORD 기록
ord-a32ac53f504a4e81ad47c98644cc799a
출처 데이터셋
uspto-grants-1995_03
특허 번호
US05401756

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