3-(Chloromethyl)pyridine hydrochloride → 7-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

반응식

[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][NH:8][C:9]2=[O:12])=[CH:4][CH:3]=1.Cl.Cl[CH2:15][C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1>>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][N:8]([CH2:15][C:16]3[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=3)[C:9]2=[O:12])=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 233943-(Chloromethyl)pyridine hydrochloride

HCID 222653177-bromo-2H-phthalazin-1-one

생성물 1

HCID 544303767-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

실험 절차

The titled compound was prepared from 7-bromo-1 (2H)-phthalazinone and 3-chloromethylpyridine hydrochloride in the same manner as in Example 10 (1) a).

출처 및 근거

ORD 기록: ord-1d6077715b0f46e3b664ef594bcac4f8
출처 데이터셋: uspto-grants-1995_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05401756

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