1,3-Dichloroacetone → HCID 22259331, 화합물

HRID 1610953노트

반응식

HRID 1610953 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([NH2:12])=[O:11])=[CH:4][C:3]=1[F:13].[Cl:14][CH2:15][C:16]([CH2:18]Cl)=O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[O:11][CH:18]=[C:16]([CH2:15][Cl:14])[N:12]=2)=[CH:4][C:3]=1[F:13]

참가 물질

3

반응물 2

HCID 107931,3-DichloroacetoneHCID 22259286HCID 22259286, 화합물

생성물 1

HCID 22259331HCID 22259331, 화합물수율 41.9%

실험 절차

Using (E)-3-(4-chloro-3-fluorophenyl)-2-propenamide (8.67 g) and 1,3-dichloroacetone (11.0 g), the same reaction as Reference Example 1-(ii) was carried out to yield the titled compound (4.95 g) as colorless flaky crystals.

후처리

  1. customthe same reaction as Reference Example 1-(ii)

출처 및 근거

ORD 기록
ord-2ecf40f2f4e449c2bb3a6293d80ae2b2
출처 데이터셋
uspto-grants-2006_01
특허 번호
US06984653B2

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