Triethylamine → Ssr-180711

HRID 1611238

반응식

HRID 1611238 반응식
[N:1]12[CH2:9][CH2:8][CH:5]([CH2:6][CH2:7]1)[NH:4][CH2:3][CH2:2]2.C(N(CC)CC)C.Cl[C:18]([O:20][C:21]1[CH:26]=[CH:25][C:24]([Br:27])=[CH:23][CH:22]=1)=[O:19]>ClCCl>[N:1]12[CH2:9][CH2:8][CH:5]([CH2:6][CH2:7]1)[N:4]([C:18]([O:20][C:21]1[CH:26]=[CH:25][C:24]([Br:27])=[CH:23][CH:22]=1)=[O:19])[CH2:3][CH2:2]2

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 3984071,4-Diazabicyclo(3.2.2)nonaneHCID 52377364-Bromophenyl chloroformate

생성물 1

HCID 9797360Ssr-180711

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

반응 조건

온도
0 °C

실험 절차

0.379 g (3.0 mmol) of 1,4-diazabicyclo[3.2.2]nonane and 0.84 ml (6.0 mmol) of triethylamine in 5 ml of dichloromethane are introduced into a 50-ml three-necked flask, the mixture is cooled to 0° C., 0.730 mg (3.1 mmol) of 4-bromophenyl chloroformate in solution in 3 ml of dichloromethane is added dropwise and the stirring is maintained at 0° C. for 10 min.

후처리

  1. temperaturethe stirring is maintained at 0° C. for 10 min.

출처 및 근거

ORD 기록
ord-8d2c8fa26d724ab3b23780235a06e1f5
출처 데이터셋
uspto-grants-2006_01
특허 번호
US06987106B1

연결된 노트

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