Bromomethylcyclopropane → HCID 483496, 화합물

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[CH:1]([C:4]1[C:5](=[O:20])[NH:6][C:7](=[O:19])[NH:8][C:9]=1[S:10][C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].Br[CH2:22][CH:23]1[CH2:25][CH2:24]1>>[CH:23]1([CH2:22][N:8]2[C:9]([S:10][C:11]3[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=3)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:20])[NH:6][C:7]2=[O:19])[CH2:25][CH2:24]1

참가 물질

반응물 2

HCID 81503Bromomethylcyclopropane

HCID 104937275-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione

생성물 1

HCID 483496HCID 483496, 화합물수율 49.4%

실험 절차

5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and bromomethyl cyclopropane were reacted by the same way with the example 1 to obtain the titled compound (170 mg, yield: 49.4%).

출처 및 근거

ORD 기록: ord-2ca16d67ddb5465d94b9b8061e966cba
출처 데이터셋: uspto-grants-2006_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06987114B1

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