Dimethyloctadecylamine → N-(2-(Benzoyloxy)ethyl)-N,N-dimethyl-n-octadecylammonium bromide

HRID 1613701

반응식

HRID 1613701 반응식
[C:1]([O:9][CH2:10][CH2:11][Br:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:13][N:14]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH3:15]>C(#N)C>[Br-:12].[C:1]([O:9][CH2:10][CH2:11][N+:14]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])([CH3:13])[CH3:15])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 15365DimethyloctadecylamineHCID 5230902-Bromoethyl Benzoate

생성물 1

HCID 19774320N-(2-(Benzoyloxy)ethyl)-N,N-dimethyl-n-octadecylammonium bromide

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A mixture of 45.0 g (0.1964 mol) of 2-bromoethyl benzoate and an equimolar amount of N,N-dimethyl-n-octadecylamine in 207 ml of acetonitrile was heated at reflux for 4.5 hours. The reaction mixture was then cooled. The solid was then collected, washed with ether, and dried to yield 76.7 g of the title compound; mp=87°-93° C.

후처리

  1. temperatureat reflux for 4.5 hours
  2. temperatureThe reaction mixture was then cooled
  3. customThe solid was then collected
  4. washwashed with ether
  5. customdried

출처 및 근거

ORD 기록
ord-5d30a4eeed0a41b5be19d5faad877ab9
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05194472

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