Glycidyl methacrylate → HCID 86744516, 화합물

HRID 1613829노트

반응식

HRID 1613829 반응식
[H-].[Na+].[C:3]([C:6]1[CH:19]=[CH:18][C:17]2[S:16][C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]=2[CH:7]=1)(=[O:5])[CH3:4].[C:20]([O:25][CH2:26][CH:27]1[O:29][CH2:28]1)(=[O:24])[C:21]([CH3:23])=[CH2:22]>O1CCCC1>[C:20]([O:25][CH2:26][CH:27]([OH:29])[CH2:28][C:7]1[C:8]2[NH:9][C:10]3[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=3)[S:16][C:17]=2[CH:18]=[CH:19][C:6]=1[C:3](=[O:5])[CH3:4])(=[O:24])[C:21]([CH3:23])=[CH2:22]

참가 물질

5

반응물 3

HCID 7837Glycidyl methacrylateHCID 24758Sodium hydrideHCID 81131Methyl phenothiazin-2-yl ketone

생성물 1

HCID 86744516HCID 86744516, 화합물수율 72.3%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매2회

실험 절차

0.20 g (0.0086 mol) of sodium hydride was added carefully to a solution of 2-acetylphenothiazine (2 g, 0.0083 mol) in 150 ml tetrahydrofuran under agitation below 5° C. A solution of glycidyl methacrylate (1.88 g, 0.013 mol) in 10 ml tetrahydrofuran was added dropwise to above solution. The reaction was kept at room temperature for 48 hours. After the solvent was removed, the residue was washed with dilute HCl and water. Dried. 2.3 g of product was obtained by recrystallization with ethyl acetate.

후처리

  1. customAfter the solvent was removed
  2. washthe residue was washed with dilute HCl and water
  3. customDried

출처 및 근거

ORD 기록
ord-7bb27ed23ed640189b7960d34b21c915
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05194544

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