Dopamine → HCID 19773395, 화합물

HRID 1614252노트

반응식

HRID 1614252 반응식
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[NH2:16][CH2:17][CH2:18][C:19]1C=C[C:23]([OH:24])=[C:21](O)[CH:20]=1.[ClH:27].O1C=CC=C1CCN>>[ClH:27].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([NH:16][CH2:17][CH2:18][C:19]1[O:24][CH:23]=[CH:21][CH:20]=1)[CH2:10]2)(=[O:3])[CH3:2]

참가 물질

4

반응물 3

HCID 681DopamineHCID 130455482-(Furan-2-yl)ethan-1-amine hydrochlorideHCID 148364565-Acetylamino-2-tetralone

생성물 1

HCID 19773395HCID 19773395, 화합물

실험 절차

Starting from 0.61 g (0.0031 mol) of 5-acetylamino-2-tetralone and 0.9 g (0.006 mol) of 2 (2-furyl)ethylamine-hydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 0.8 g (77.1% of theory) and with a melting point of 256° C., which increases to 257° C. after recrystallisation from methanol/ether.

출처 및 근거

ORD 기록
ord-4792ae63847248e18762df49d636f09b
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05196454

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