N-Iodosuccinimide → HCID 67607194, 화합물
반응식
[CH:1]1([CH2:4][N:5]2[C:9]3[CH:10]=[CH:11][C:12]([OH:14])=[CH:13][C:8]=3[N:7]=[N:6]2)[CH2:3][CH2:2]1.[I:15]N1C(=O)CCC1=O>C(O)(=O)C.O>[CH:1]1([CH2:4][N:5]2[C:9]3[CH:10]=[CH:11][C:12]([OH:14])=[C:13]([I:15])[C:8]=3[N:7]=[N:6]2)[CH2:2][CH2:3]1참가 물질
5
실험 절차
1-(Cyclopropylmethyl)-1H-benzotriazol-5-ol (5.41 g, 28.6 mmol) was dissolved in acetic acid (75 mL) and treated with N-iodosuccinimide (4.79 g, 21.3 mmol, 0.74 equiv) portionwise. After 15 minutes, the mixture was diluted with water (150 mL) and extracted with dichloromethane (2×100 mL). The combined organic extracts were dried with sodium sulfate, filtered and concentrated in vacuo, providing the titled compound.
후처리
- extractionextracted with dichloromethane (2×100 mL)
- dry with materialThe combined organic extracts were dried with sodium sulfate
- filtrationfiltered
- concentrationconcentrated in vacuo
출처 및 근거
- ORD 기록
- ord-a9fc3005cc424af29305c22084fffc0b
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08772276B2
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