Butanal → 1-propyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
반응식
[NH2:1][C@H:2]([C:13]([OH:15])=[O:14])[CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1.O.OS(O)(=O)=O.[CH:22](=O)[CH2:23][CH2:24][CH3:25]>C(O)C>[CH2:23]([CH:22]1[C:5]2[NH:6][C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:4]=2[CH2:3][CH:2]([C:13]([OH:15])=[O:14])[NH:1]1)[CH2:24][CH3:25]참가 물질
6
실험 절차
L-tryptophan (5.10 g, 25 mmol), water (300 ml), H2SO4 (0.5M, 50 ml), n-butyraldehyde (10 ml) and ethanol (100 ml) were added in a 250 ml round-bottom flask, and then stirred and reacted at room temperature for 24 h. After filtration, wash with water and drying, white solids (3.75 g, 58%) were obtained.
후처리
- customreacted at room temperature for 24 h
- filtrationAfter filtration
- washwash with water
- customdrying
출처 및 근거
- ORD 기록
- ord-412de87610234ca8bc04e06223598e84
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08772311B2
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