Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-hydroxy-N-(5-(methylsulfinyl)thiazol-2-yl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-(5-(Methylsulfinyl)thiazol-2-ylcarbamoyl)phenyl acetate | HCID 56969397 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-hydroxy-N-(5-(methylsulfinyl)thiazol-2-yl)benzamide | HCID 56969615 | — |
반응 단계
A solution of 11 (1.0 g, 3.1 mmol) is dissolved in THF (20 mL) and is added under stirring to 2M HCl (100 mL). The reaction is refluxed for one hour and is allowed to cool under stirring over one hour. The product is filtered using a sintered glass funnel, washed with distilled water and THF and dried in high vacuum and affords 12 as a colorless solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08772502B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-7aab2f2e0d7e4a35b9fb58228235f10f |
| 출처 메모 | uspto-grants-2014_07 |