反应详情

A solution of 11 (1.0 g, 3.1 mmol) is dissolved in THF (20 mL) and is added under stirring to 2M HCl (100 mL). The reaction is refluxed for one hour and is allowed to cool under stirring over one hour. The product is filtered using a sintered glass funnel, washed with distilled water and THF and dried in high vacuum and affords 12 as a colorless solid.

1. additionis added
2. temperatureThe reaction is refluxed for one hour
3. temperatureto cool
4. filtrationThe product is filtered
5. washwashed with distilled water and THF
6. customdried in high vacuum