N-bromobutanimide → Methyl 3-bromo-5-formyl-4-hydroxybenzoate

HRID 1622098노트

반응식

HRID 1622098 반응식
[CH:1]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[OH:13])[C:6]([O:8][CH3:9])=[O:7])=[O:2].[Br:14]N1C(=O)CCC1=O>>[Br:14][C:11]1[CH:10]=[C:5]([CH:4]=[C:3]([CH:1]=[O:2])[C:12]=1[OH:13])[C:6]([O:8][CH3:9])=[O:7]

참가 물질

3

반응물 2

HCID 67184N-bromobutanimideHCID 212595Benzoic acid, 3-formyl-4-hydroxy-, methyl ester

생성물 1

HCID 71711084Methyl 3-bromo-5-formyl-4-hydroxybenzoate수율 73%

실험 절차

Proceeding as in Reference 9, but substituting methyl 3-formyl-4-hydroxybenzoate (12.0 g, 66.6 mmol, 1 eq.) and N-bromosuccinimide (12.45 g, 69.9 mmol, 1.05 eq.) gave methyl 3-bromo-5-formyl-4-hydroxybenzoate (12.6 g) as a white solid.

출처 및 근거

ORD 기록
ord-bce687a42dca4da0ad2ab72bae90c576
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08778625B2

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