Iodine → HCID 86666998, 화합물
반응식
[Cl:1][C:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[S:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[I:16]I>C(Cl)(Cl)Cl>[I-:16].[Cl:1][C:2]1[C:15]2[C:6](=[S+:7][C:8]3[C:13]([N:14]=2)=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1참가 물질
4
반응 조건
- 온도
- 5 °C
실험 절차
1-Chlorophenothiazine (664 mg, 2.84 mmol) was dissolved in CHCl3 (50 mL) and cooled to 5° C. The solution was stirred as a solution of I2 (2.16 g, 8.51 mmol) dissolved in CHCl3 (10 mL) was added dropwise. The mixture was stirred at 5° C. overnight and allowed to warm to RT. The solvent was evaporated to dryness. The residue was stirred in Et2O and was filtered off and washed with Et2O until the filtrate was colorless. The dark solid was dried under vacuum and used without purification.
후처리
- additionwas added dropwise
- temperatureto warm to RT
- customThe solvent was evaporated to dryness
- stirringThe residue was stirred in Et2O
- filtrationwas filtered off
- washwashed with Et2O until the filtrate
- customThe dark solid was dried under vacuum
- customused without purification
출처 및 근거
- ORD 기록
- ord-7f0bcd1bd2db43f7a62b9a21ad4fc290
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08785434B2
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