Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → FA amoxicillin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| 반응물 | Amoxicillin | HCID 33613 | — |
| 반응물 | 5-Aminofluorescein | HCID 76845 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | FA amoxicillin | HCID 131731698 | — |
반응 단계
Fluoresceinamine (FA; 0.0583 g) was dissolved in 1.0 ml acetonitrile to from a FA solution. Amoxicillin (0.1 g) was dissolved in 30 ml deionized water, and mixed with the aforesaid FA solution. 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (0.0408 g) was added thereto and magnetically stirred at room temperature in the dark for 12 hours to make FA to graft to the carboxyl group of amoxicillin to form a fluorescent-labeled FA-amoxicillin. And, finally, the sample was freeze-dried to collect the fluorescent-labeled FA-amoxicillin.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08790695B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-adb1b15315a040e0ac32635795454c18 |
| 출처 메모 | uspto-grants-2014_07 |