Allyl chloroformate → HCID 12582636, 화합물

반응식

[CH2:1]([O:4][C:5]([N:7]1[CH2:17][CH2:16][C:10]2[N:11]=[N:12][C:13](Cl)=[CH:14][C:9]=2[CH2:8]1)=[O:6])[CH:2]=[CH2:3].C(O)(=O)/C=C\C(O)=O.ClC1[N:32]=[N:31]C2CCNCC=2C=1.C(OC(Cl)=O)C=C>>[CH2:1]([O:4][C:5]([N:7]1[CH2:17][CH2:16][C:10]2[N:11]=[N:12][C:13]([NH:31][NH2:32])=[CH:14][C:9]=2[CH2:8]1)=[O:6])[CH:2]=[CH2:3]

참가 물질

반응물 3

HCID 18052Allyl chloroformate

HCID 541038892-Propen-1-yl 3-chloro-7,8-dihydropyrido[4,3-c]pyridazine-6(5H)-carboxylate

HCID 86733381HCID 86733381, 화합물

생성물 1

HCID 12582636HCID 12582636, 화합물

실험 절차

The 3-chloro-5,6,7,8-tetrahydro-6-pyrido [4,3-c]pyridazinecarboxylic acid allyl ester, required as starting material, may be obtained in a manner analogous to that described in Example 8(g), from 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and chloroformic acid allyl ester. The oily crude product is used for the next reaction without purification.