Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aniline → 2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl- | HCID 84657 | — |
반응 단계
2-fluoronitrobenzene was treated with aniline in the prescence of K2CO3 in CH3CN and heated to reflux for 12 h. The solution is cooled, filtered and the solvent removed. The nitro group is reduced with catalytic hydrogenation and the diamine treated with CDI to give 1-phenyl-1,3-dihydro-benzoimidazol-2-one.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06506738B1 |
| 출처 데이터셋 | uspto-grants-2003_01 |
| ORD ID | ord-6ce79da2204742599c88902fe82d6331 |
| 출처 메모 | uspto-grants-2003_01 |