Benzoyl Peroxide → HCID 18675872, 화합물

HRID 1635088노트

반응식

HRID 1635088 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH3:8])[C:3]=1[O:9][CH3:10].[Br:11]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH2:8][Br:11])[C:3]=1[O:9][CH3:10]

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 105830464-Chloro-3-methoxy-2-methylpyridine

생성물 1

HCID 18675872HCID 18675872, 화합물

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

4-Chloro-3-methoxy-2-methyl-pyridine (6.12 g) is dissolved in carbon tetrachloride (80 ml) then N-bromo-succinimide (7.12 g) and benzoyl peroxide (1 g) are added. The reaction mixture is refluxed under UV irradiation for 1.5 hour. The solid is filtered after cooling and the solvent evaporated. The desired product is purified by chromatography on silica gel.

후처리

  1. temperatureThe reaction mixture is refluxed under UV irradiation for 1.5 hour
  2. filtrationThe solid is filtered
  3. temperatureafter cooling
  4. customthe solvent evaporated
  5. customThe desired product is purified by chromatography on silica gel

출처 및 근거

ORD 기록
ord-6591c0c517204113a4c93daf9a5f06cb
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06509349B1

반응 노트

불러오는 중…