tert-Butyl (4-(furan-3-yl)-2-nitrophenyl)carbamate → (2-Amino-4-furan-3-yl-phenyl)-carbamic acid tert.-butyl ester

HRID 1635186노트

반응식

HRID 1635186 반응식
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][O:16][CH:15]=2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][O:16][CH:15]=2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 1

HCID 69592767tert-Butyl (4-(furan-3-yl)-2-nitrophenyl)carbamate

생성물 1

HCID 69592861(2-Amino-4-furan-3-yl-phenyl)-carbamic acid tert.-butyl ester

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

Prepared from (4-furan-3-yl-2-nitrophenyl)-carbamic acid tert.-butyl ester (Example B6) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a light brown solid. (744 mg).

후처리

  1. customObtained as a light brown solid

출처 및 근거

ORD 기록
ord-ca6ed3d5cb884179b2474a6b91b9791b
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06509328B1

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