Cinchomeronic acid → 1H,3H-furo(3,4-c)pyridine-1,3-dione

HRID 1636323

반응식

HRID 1636323 반응식
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([OH:9])=O)=[C:3]([C:10]([OH:12])=[O:11])[CH:2]=1>C(OC(=O)C)(=O)C>[N:1]1[CH:6]=[CH:5][C:4]2[C:7]([O:12][C:10](=[O:11])[C:3]=2[CH:2]=1)=[O:9]

참가 물질

3

반응물 1

HCID 10273Cinchomeronic acid

생성물 1

HCID 2783981H,3H-furo(3,4-c)pyridine-1,3-dione수율 75.5%

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A mixture of 3,4-pyridine-dicarboxylic acid (15 g) and acetic anhydride (30 ml) is refluxed for 2 hours. The acetic anhydride in excess is distilled off and the residue is purified by sublimation (123° C. at 3 mmHg) to give 10.1 g of 3,4-pyridine-dicarboxylic acid anhydride, a white solid, m.p. 74-76° C.

후처리

  1. temperatureis refluxed for 2 hours
  2. distillationThe acetic anhydride in excess is distilled off
  3. customthe residue is purified by sublimation (123° C. at 3 mmHg)

출처 및 근거

ORD 기록
ord-295789ffbf0143ab9a2269b289a48499
출처 데이터셋
uspto-grants-2000_03
특허 번호
US06034092

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