Sodium Hydroxide → (E)-3-[4-(3-Dimethylaminopropenyl)phenyl]acrylic Acid

HRID 1637884노트

반응식

HRID 1637884 반응식
[CH3:1][N:2]([CH3:18])[CH2:3][CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]([O:16]C)=[O:15])=[CH:8][CH:7]=1.[OH-].[Na+]>CO>[CH3:18][N:2]([CH3:1])[CH2:3][CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]([OH:16])=[O:15])=[CH:8][CH:7]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 86755260(E)-3-[4-(3-dimethylaminopropenyl)phenyl]acrylic acid, methyl ester

생성물 1

HCID 70098974(E)-3-[4-(3-Dimethylaminopropenyl)phenyl]acrylic Acid수율 85%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

This product was prepared by refluxing for four hours, (E)-3-[4-(3-dimethylaminopropenyl)phenyl]acrylic acid, methyl ester with NaOH (0.16 g, 2 equiv.) in 10 mL of MeOH. After evaporation of the solvent in vacuo, treatment with 5 mL of HCl (1N) gave the title compound (0.4 g, 85%) as a gummy orange solid.

후처리

  1. customThis product was prepared
  2. temperatureby refluxing for four hours
  3. customAfter evaporation of the solvent in vacuo, treatment with 5 mL of HCl (1N)

출처 및 근거

ORD 기록
ord-5f1af7ce008f423e87cf0593116f4905
출처 데이터셋
uspto-grants-2000_03
특허 번호
US06043252

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