Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
P-Toluic Acid → HCID 178473962, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | P-Toluic Acid | HCID 7470 | — |
| 반응물 | 1-Hydroxybenzotriazole | HCID 75771 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| 반응물 | 1-Acetyl-5-nitroindolin-2-one | HCID 2839329 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 178473962 | HCID 178473962 | — |
반응 단계
Prepared analogously to Example 10(a) from 1-acetyl-5-nitro-2-indolinone and 4-methyl-benzoic acid in dry DMF in the presence of TBTU, HOBT and Hunig's base (20° C., overnight) and final purification by column chromatography on silica gel with CH2Cl2 as eluant.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06043254 |
| 출처 데이터셋 | uspto-grants-2000_03 |
| ORD ID | ord-cfac0bb4acbb4dc58561b1a882d56e8f |
| 출처 메모 | uspto-grants-2000_03 |