Ethambutol Hydrochloride → Ethambutol

HRID 1643530

반응식

HRID 1643530 반응식
[CH3:1][CH2:2][C@H:3]([NH:6][CH2:7][CH2:8][NH:9][C@H:10]([CH2:13][OH:14])[CH2:11][CH3:12])[CH2:4][OH:5].Cl.Cl>C(=O)([O-])[O-].[Na+].[Na+].[OH-].[Na+]>[CH3:12][CH2:11][C@H:10]([NH:9][CH2:8][CH2:7][NH:6][C@H:3]([CH2:4][OH:5])[CH2:2][CH3:1])[CH2:13][OH:14]

참가 물질

4

반응물 1

HCID 14051Ethambutol Hydrochloride3회

생성물 1

HCID 14052Ethambutol

시약·촉매·용매 2

HCID 10340Sodium Carbonate용매HCID 14798Sodium Hydroxide용매

실험 절차

Ethambutol Dihydrochloride (ETB) is obtained from MP Biomedicals (Aurora, Ohio). ETB (7 grams) are dissolved in 100 mL of a saturated solution of sodium carbonate in 5M NaOH. The solution is stirred for 10 minutes and the free based ETB is extracted with three volumes of chloroform. The solution is dried over sodium sulfate. After filtration, the chloroform is removed by rotary evaporation. Ethambutol is represented in the structure below (a).

후처리

  1. extractionis extracted with three volumes of chloroform
  2. dry with materialThe solution is dried over sodium sulfate
  3. filtrationAfter filtration
  4. customthe chloroform is removed by rotary evaporation

출처 및 근거

ORD 기록
ord-bc6a8db3687a4cab96373542461f07a9
출처 데이터셋
uspto-grants-2012_02
특허 번호
US08119840B2

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