Dichloromethane → HCID 380419, 화합물

HRID 1645409노트

반응식

HRID 1645409 반응식
[CH2:1]1[S:9](=[O:11])(=[O:10])[O:8][CH2:7][CH2:6][O:5][S:2]1(=[O:4])=[O:3].[H-].[Na+].C1C=CC(S(N(S(C2C=CC=CC=2)(=O)=O)[F:24])(=O)=O)=CC=1.C(Cl)Cl>C1COCC1.CC#N.C1CCCCC1>[F:24][CH:1]1[S:2](=[O:3])(=[O:4])[O:5][CH2:6][CH2:7][O:8][S:9]1(=[O:11])=[O:10]

참가 물질

8

반응물 4

HCID 6344DichloromethaneHCID 24758Sodium hydrideHCID 57513CyclodisoneHCID 588007N-Fluorobenzenesulfonimide

생성물 1

HCID 380419HCID 380419, 화합물수율 15.3%

시약·촉매·용매 3

HCID 6342Acetonitrile용매HCID 8028Tetrahydrofuran용매HCID 8078Cyclohexane용매

실험 절차

To a solution of 2.4 g of ethylene methanedisulfonate in 20 mL of THF and 0.35 g of NaH was added 3.8 g of N-fluorobenzene sulfonimide in 25 mL of CH3CN. The product was isolated by crystallization from CH2Cl2 and cyclohexane to give 0.4 g of ethylene fluoromethane disulfonate which was brominated in H2O to give ethylene fluorobromomethanedisulfonate, m.p. 82-90° C. (93-3).

출처 및 근거

ORD 기록
ord-f75b0f44aa064d5abe0be21fdf0cc7b8
출처 데이터셋
uspto-grants-2012_02
특허 번호
US08124793B2

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