Hydrochloric Acid → N-[[2-(Phosphonomethyl)phenyl]methyl]glycine, hydrochloride

HRID 1646179노트

반응식

HRID 1646179 반응식
C([O:3][P:4]([CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:16][NH:17][CH2:18][C:19]([O:21]C)=[O:20])([O:6]CC)=[O:5])C.[ClH:23]>>[ClH:23].[P:4]([CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:16][NH:17][CH2:18][C:19]([OH:21])=[O:20])([OH:6])([OH:5])=[O:3]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 19801611HCID 19801611, 화합물

생성물 1

HCID 85635052N-[[2-(Phosphonomethyl)phenyl]methyl]glycine, hydrochloride

실험 절차

A solution of methyl N-[[2[(diethoxyphosphinyl)methyl]phenyl]methyl]glycinate (Example 1) (0.5 g, 1.5 mmol) in 6N hydrochloric acid solution (10 ml) is stirred at reflux in an oil bath for 18 hours. The water is removed in vacuo to give 0.4 g of a white solid.

후처리

  1. temperatureat reflux in an oil bath for 18 hours
  2. customThe water is removed in vacuo

출처 및 근거

ORD 기록
ord-3cbc00c8eb004dacb065bb8bafcc3c18
출처 데이터셋
uspto-grants-1993_01
특허 번호
US05179085

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