Water → 2-Sulfamoyl-6-benzothiazolyl acetate

HRID 1649386노트

반응식

HRID 1649386 반응식
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10]([NH2:13])(=[O:12])=[O:11].O.O.[C:16]([O-:19])(=[O:18])[CH3:17].[Li+].[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O.[K+].[K+].O>C(O)(=O)C.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[C:16]([O:19][C:7]1[CH:8]=[CH:9][C:4]2[N:3]=[C:2]([S:10](=[O:12])(=[O:11])[NH2:13])[S:1][C:5]=2[CH:6]=1)(=[O:18])[CH3:17]

참가 물질

7

반응물 4

HCID 962WaterHCID 24502Potassium DichromateHCID 679442-BenzothiazolesulfonamideHCID 23666338Lithium acetate dihydrate

생성물 1

HCID 132366622-Sulfamoyl-6-benzothiazolyl acetate

시약·촉매·용매 2

HCID 167845palladium(II) acetate촉매HCID 176Acetic Acid용매

실험 절차

A stirred solution of benzothiazole-2-sulfonamide (2.14 g, 0.01 mole), palladium acetate (2.25 g, 0.01 mole), lithium acetate dihydrate (1.65, 0.025 mole) and potassium dichromate (5.9 g, 0.02 mole) in acetic acid (25 ml) is heated on a steam bath for 24 hours then poured into H2O (100 ml) to give 2-sulfamoyl-6-benzothiazolyl acetate which melts at 193°-4° C. after recrystallization from 2-propanol.

출처 및 근거

ORD 기록
ord-08a811ec83da470191a4a1c8cd779c04
출처 데이터셋
uspto-grants-1983_11
특허 번호
US04416890

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