Imidazole → 1-[2-(2-Naphthyl)ethyl]imidazole

HRID 1649388

반응식

HRID 1649388 반응식
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.Br[CH2:7][CH2:8][C:9]1[CH:18]=[CH:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=1.CC(C)([O-])C.[K+]>C(O)CCC>[CH:10]1[C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:17]=[CH:18][C:9]=1[CH2:8][CH2:7][N:1]1[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

5

반응물 3

HCID 795ImidazoleHCID 2282702-(2-Bromoethyl)naphthaleneHCID 23665647Potassium tert-butoxide

생성물 1

HCID 30589261-[2-(2-Naphthyl)ethyl]imidazole

시약·촉매·용매 1

HCID 2631-Butanol용매

실험 절차

A mixture of imidazole (1.02 g, 0.015 mol), 2-(2-bromoethyl)naphthalene (3.53 g, 0.015 mol) and potassium tert-butoxide (1.68 g, 0.015 mol) in dry butan-1-ol (100 ml) was stirred and heated under reflux for 29 h.

후처리

  1. temperatureheated
  2. temperatureunder reflux for 29 h.

출처 및 근거

ORD 기록
ord-b6f00ae32a464cf2b734127cc1bf5b49
출처 데이터셋
uspto-grants-1983_11
특허 번호
US04416895

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