HCID 14076002, 화합물 → HCID 14076005, 화합물

HRID 1649624노트

반응식

HRID 1649624 반응식
[CH3:1][C:2]([CH3:16])([C:4](=[O:15])[C:5]#[C:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH3:3].[H][H]>CO.[Ni]>[CH3:3][C:2]([CH3:16])([C:4](=[O:15])[CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)[CH3:1]

참가 물질

5

반응물 2

HCID 14076002HCID 14076002, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 14076005HCID 14076005, 화합물수율 95.7%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

20 g (0.0926 mol) of 2,2-dimethyl-6-phenoxy-hex-4-in-3-one are dissolved in 180 ml of methanol, and 5 g of Raney nickel are added. The mixture is hydrogenated with hydrogen under a pressure of 50 to 60 bar at 37° C. The hydrogenation has ended after 40 minutes. The reaction mixture is filtered and the filtrate is concentrated by stripping off the solvent under reduced pressure. 19.5 g (95.7% of theory) of 2,2-dimethyl-6-phenoxy-hexan-3-one are obtained in this manner.

후처리

  1. filtrationThe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated

출처 및 근거

ORD 기록
ord-36b585179e6b4d1b8db7f859de431403
출처 데이터셋
uspto-grants-1990_05
특허 번호
US04921529

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