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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Piperidine → HCID 178431711, 화합물

HRID 1651975
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HRID 1651975 반응식
C1CCNCC1.CC1(C)OC(=O)C(Oc2ccc(Br)cn2)=C1c1ccc(S(C)(=O)=O)cc1>C1CN2CCN1CC2.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.COCCOC.CS(C)=O.F[P-](F)(F)(F)(F)F.Fc1cc(F)c(-c2ccc(C(F)(F)F)cn2)[c]([Ir+][c]2cc(F)cc(F)c2-c2ccc(C(F)(F)F)cn2)c1.[Cl][Ni][Cl]>CC1(C)OC(=O)C(Oc2ccc(N3CCCCC3)cn2)=C1c1ccc(S(C)(=O)=O)cc1
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참가 물질

7

반응물 2

HCID 8082PiperidineHCID 99328283-((5-Bromopyridin-2-yl)oxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one

생성물 1

HCID 178431711HCID 178431711, 화합물수율 1.64%

시약·촉매·용매 4

HCID 9237Dabco촉매HCID 15773433Dichloronickel;1,2-dimethoxyethane촉매HCID 178441141HCID 178441141, 화합물촉매HCID 679Dimethyl Sulfoxide용매3회

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온도
55 °C

후처리

  1. additionThe samples was moved from a 1536 well plate into a 384 well plate. The 384 well plate contained 75 microliter of 1% Acetic acid in DMSO solution with 0.003M trimethoxybenzene. The reaction plate was rinsed three times with the same solution to make a total addition volume of ~90 microliters
  2. aliquot25 microliter of quenched reaction mixture was taken
  3. additionTo the 25 microliter aliquot 50 microliter of DMSO was added. If the original reaction concentration was 0.05 M (wrt limiting reagent). This would make a final analytical concentration of 0.36 mM which is in line with typical analytical concentrations from this group.

출처 및 근거

ORD 기록
ord-cb734ab9d0034dc99ce1c8c57ff8ed27
출처 데이터셋
Nano CN PhotoChemistry Informers Library
DOI
10.1021/acs.accounts.0c00760
원본 링크
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