Methyl iodide → HCID 20080576, 화합물

반응식

[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2([OH:23])[CH2:20][CH2:19][O:18][C:17]([CH3:22])([CH3:21])[CH2:16]2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:24]I>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2([O:23][CH3:24])[CH2:20][CH2:19][O:18][C:17]([CH3:21])([CH3:22])[CH2:16]2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 6328Methyl iodide

HCID 200806534-(3-Benzyloxyphenyl)-4-hydroxy-2,2-dimethyltetrahydropyran

생성물 1

HCID 20080576HCID 20080576, 화합물수율 89%

실험 절차

Using the procedure described in Example 3, 4-(3-benzyloxyphenyl)-4-hydroxy-2,2-dimethyltetrahydropyran (1.14 g) was reacted with methyl iodide (0.25 ml) to give 4-(3-benzyloxyphenyl)-4-methoxy-2,2-dimethyltetrahydropyran (1.06 g, 89%), as an oil.

출처 및 근거

ORD 기록: ord-811f6eb78a424920984e096bc5807855
출처 데이터셋: uspto-grants-1995_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05403859

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