Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 8-(3-Trifluoromethylphenyl)-6-(4-trifluoromethylphenyl)pyrido[2,3-d]pyridazin-5-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 4-(Trifluoromethyl)phenylhydrazine | HCID 136200 | — |
| 반응물 | 2-(3-Trifluoromethylbenzoyl)nicotinic acid | HCID 20078895 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 8-(3-Trifluoromethylphenyl)-6-(4-trifluoromethylphenyl)pyrido[2,3-d]pyridazin-5-one | HCID 20078892 | — |
반응 단계
A suspension of 2-(3-trifluoromethylbenzoyl)nicotinic acid (1.5 g) and 4-trifluoromethylphenylhydrazine (1.34 g) in toluene was stirred at reflux temperature for 3 hours (water was removed azeotropically from the mixture).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05405826 |
| 출처 데이터셋 | uspto-grants-1995_04 |
| ORD ID | ord-64ecef6e5d66456da5d6e3b2af2269ae |
| 출처 메모 | uspto-grants-1995_04 |