Sodium Hydroxide → HCID 21533366, 화합물
반응식
C([O:3][C:4]([C:6]1[C:15](=[O:16])[C:14]2[C:9](=[CH:10][C:11]([CH:19]3[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]3)=[C:12]([O:17][CH3:18])[CH:13]=2)[N:8]([CH2:25][CH3:26])[CH:7]=1)=[O:5])C.[OH-].[Na+]>C(O)C>[CH2:25]([N:8]1[C:9]2[C:14](=[CH:13][C:12]([O:17][CH3:18])=[C:11]([CH:19]3[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]3)[CH:10]=2)[C:15](=[O:16])[C:6]([C:4]([OH:5])=[O:3])=[CH:7]1)[CH3:26]참가 물질
4
실험 절차
A suspension of 18.7 g of 1-ethyl-4-oxo-6-methoxy-7-cyclohexyl-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester described in Example 18, in 150 ml of ethanol and 150 ml of 2 N sodium hydroxide solution is boiled for 5 hours under reflux. The clear solution thereby produced is evaporated to dryness in vacuo. 2 N Hydrochloric acid is added to the residue. The resulting crystals are filtered off and well washed with water. 1-Ethyl-4-oxo-6-methoxy-7-cyclohexyl-1,4-dihydro-quinoline-3-carboxylic acid, thus obtained, melts at 176°-178°C.