Methyl vinyl ketone → Piperitenone

HRID 1657541

반응식

HRID 1657541 반응식
[CH:1]([C:3]([CH3:5])=O)=[CH2:2].O=[C:7]([CH:9]=[C:10]([CH3:12])[CH3:11])[CH3:8].[OH-:13].[K+]>O1CCCC1>[CH3:5][C:3]1[CH2:8][CH2:7][C:9](=[C:10]([CH3:12])[CH3:11])[C:2](=[O:13])[CH:1]=1

참가 물질

5

반응물 3

HCID 6570Methyl vinyl ketoneHCID 8858Mesityl oxideHCID 14797Potassium Hydroxide

생성물 1

HCID 381152Piperitenone

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Furthermore, J. J. Beereboom (U.S. Pat. No. 3,238,261 and J. Org. Chem., 31, 2026 (1966)) describes the reaction of methyl vinyl ketone with excess mesityl oxide in the presence of potassium hydroxide powder in tetrahydrofuran as the solvent. The piperitenone obtained is purified in a very expensive manner via the piperitenone-bisulfite adduct. In this process, yields of piperitenone of between 36 and 54% of theory are obtained.

출처 및 근거

ORD 기록
ord-d28f9dc415d6496bb51c4d7048fe8eb8
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03960970

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