Water → HCID 21447172, 화합물

HRID 1657615노트

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HRID 1657615 반응식
C[O:2][C:3]1[C:8]([O:9]C)=[CH:7][C:6]2[C:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH2:18][N:19]4[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]4)[CH2:13][C:12]=3[C:25](=[O:27])[O:26][C:5]=2[CH:4]=1.O>Br>[OH:2][C:3]1[C:8]([OH:9])=[CH:7][C:6]2[C:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH2:18][N:19]4[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]4)[CH2:13][C:12]=3[C:25](=[O:27])[O:26][C:5]=2[CH:4]=1

참가 물질

4

반응물 2

HCID 962WaterHCID 432241W10294A free base

생성물 1

HCID 21447172HCID 21447172, 화합물

시약·촉매·용매 1

HCID 260Hydrogen Bromide용매

실험 절차

A solution of 4.7 g of 1,2,3,4-tetrahydro-8,9-dimethoxy-3-(2-piperidinoethyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one in 70 cc of 48% HBr was refluxed for 17 hr and cooled. Precipitate was cryst from water affording 2.8 g of product; mp 291°-295°C.

후처리

  1. temperaturecooled

출처 및 근거

ORD 기록
ord-d0f8ae5c22e7423a99535b68e0d29f43
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03961057

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