Hydrochloric Acid → HCID 21506809, 화합물

반응식

[OH:1][C:2]1([C:9]2[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:11][C:10]=2[CH2:19]O)[CH2:7][CH2:6][N:5]([CH3:8])[CH2:4][CH2:3]1.Cl>>[CH3:8][N:5]1[CH2:6][CH2:7][C:2]2([C:9]3[C:10](=[CH:11][CH:12]=[C:13]([C:15]([F:17])([F:18])[F:16])[CH:14]=3)[CH2:19][O:1]2)[CH2:3][CH2:4]1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 867335264-Hydroxy-4-(alpha-hydroxy-4-trifluoromethyl-2-tolyl)-1-methylpiperidine

생성물 1

HCID 21506809HCID 21506809, 화합물

실험 절차

Treatment of 4-hydroxy-4-(α-hydroxy-4-trifluoromethyl-2-tolyl)-1-methylpiperidine with hydrochloric acid by the method described in Example 16d provides 1,3-dihydro-1'-methyl-6-trifluoromethylspiro[isobenzofuran-1,4'-piperidine].

출처 및 근거

ORD 기록: ord-9e703be7e72b4721bfba08501dbdf5a0
출처 데이터셋: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03962259

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