Hydrochloric Acid → HCID 21510121, 화합물

HRID 1658270노트

반응식

HRID 1658270 반응식
[NH2:1][CH2:2][CH2:3][OH:4].CO.[Cl:7][C:8]1[CH:18]=[CH:17][CH:16]=C[C:9]=1[C:10]([N+:12]([O-:14])=[O:13])=C.[ClH:19].CCO[CH2:23][CH3:24]>CC(O)C>[ClH:7].[Cl:19][C:24]1[CH:23]=[CH:16][CH:17]=[CH:18][C:8]=1[CH:9]([NH:1][CH2:2][CH2:3][OH:4])[CH2:10][N+:12]([O-:14])=[O:13]

참가 물질

7

반응물 5

HCID 313Hydrochloric AcidHCID 700EthanolamineHCID 887MethanolHCID 3283Diethyl Ether2회HCID 215101131-Chloro-2-(1-nitroethenyl)benzene

생성물 1

HCID 21510121HCID 21510121, 화합물

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

A solution of 6.1 parts of 2-aminoethanol in 16 parts of methanol and 40 parts of ether is cooled on ice. Then there is added dropwise at about 5°C. a solution of 18.4 parts of o-chloro-α-nitrostyrene in 60 parts of ether. Upon completion, stirrng in an ice-bath is continued for 1 hour. The reaction mixture is acidified with an excess of 2-propanol previously saturated with gaseous hydrogen chloride. The precipitated product is filtered off, washed thoroughly with ether and dried, yielding 2-{N-[o-chloro-α-(nitromethyl)benzyl]amino} ethanol hydrochloride.

후처리

  1. filtrationThe precipitated product is filtered off
  2. washwashed thoroughly with ether
  3. customdried

출처 및 근거

ORD 기록
ord-1eca7131afa24287bea6ad7d0a11380f
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03963718

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