Ethanolamine → Lauric acid monoethanolamide

HRID 1659896

반응식

HRID 1659896 반응식
[CH2:1]([CH2:3][NH2:4])[OH:2].[C:5](O)(=[O:17])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>C1(C)C=CC=CC=1>[OH:2][CH2:1][CH2:3][NH:4][C:5](=[O:17])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

4

반응물 2

HCID 700EthanolamineHCID 3893Lauric Acid

생성물 1

HCID 8899Lauric acid monoethanolamide

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
140 °C

실험 절차

To a solution of 24 g (0.4 mole) ethanolamine in 100 ml toluene was added 40 g (0.2) lauric acid at 50° C. The mixture was refluxed for 6 hours. Toluene was gradually removed to increase the final pot temperature to 140° C. The distillate was collected in a Stark & Dean trap. The toluene was removed by vacuum stripping and the residue was crystallized from n-hexane. The title compound (44 g) thus obtained melted at 80°-84° C.

후처리

  1. temperatureThe mixture was refluxed for 6 hours
  2. customToluene was gradually removed
  3. distillationThe distillate was collected in a Stark & Dean trap
  4. customThe toluene was removed by vacuum stripping
  5. customthe residue was crystallized from n-hexane

출처 및 근거

ORD 기록
ord-891d879642f2463097f63866a9287d86
출처 데이터셋
uspto-grants-1981_12
특허 번호
US04305868

연결된 노트

불러오는 중…