Formamide → 4-chloroisoindole-1,3-dione
반응식
[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:4]2[C:5]([O:7][C:8](=O)[C:3]=12)=[O:6].C([NH2:15])=O>O>[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:4]2[C:5]([NH:15][C:8](=[O:7])[C:3]=12)=[O:6]참가 물질
4
반응 조건
- 온도
- 100 °C
실험 절차
(b 1) 300 parts of 3-chlorophthalic anhydride in 1,200 parts by volume of formamide are stirred for 2 hours at 140° C. The mixture is then allowed to cool to 100° C. after which the solution is poured into 5,000 parts by volume of water. The precipitate which forms is filtered off, washed with water and dried under reduced pressure. 275 parts (92.2% of theory) of 3-chlorophthalimide, of melting point 236°-238° C., are obtained.
후처리
- filtrationThe precipitate which forms is filtered off
- washwashed with water
- customdried under reduced pressure
출처 및 근거
- ORD 기록
- ord-13844a440a624164881cb39fa99eb1bf
- 출처 데이터셋
- uspto-grants-1981_12
- 특허 번호
- US04306074
반응 노트
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