N-Hydroxyphthalimide → O-[(5-chlorothiophen-2-yl)methyl]hydroxylamine

HRID 1663120노트

반응식

HRID 1663120 반응식
[OH:1][N:2]1C(=O)C2=CC=CC=C2C1=O.[Cl:13][C:14]1[S:15][C:16]([CH2:19]Cl)=[CH:17][CH:18]=1>>[Cl:13][C:14]1[S:15][C:16]([CH2:19][O:1][NH2:2])=[CH:17][CH:18]=1

참가 물질

3

반응물 2

HCID 10665N-HydroxyphthalimideHCID 5830792-Chloro-5-(chloromethyl)thiophene

생성물 1

HCID 10986580O-[(5-chlorothiophen-2-yl)methyl]hydroxylamine

실험 절차

Prepared by a similar procedure as described for preparation 15. Starting materials: N-hydroxyphthalimide and 2-chloro-5-(chloromethyl)thiophene (Aldrich). 13C-NMR (DMSO-d6) δ 140.2, 127.9, 126.3, 126.0, 71.1.

후처리

  1. customPrepared by a similar procedure
  2. customas described for preparation 15

출처 및 근거

ORD 기록
ord-03d2ae0217664db097dda48cb400b540
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08034811B2

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